Plants have resisted attacks by animals to eat them in various ways. Most notably, they have grown thorns or thrown off toxic chemicals. It has taken millions of years through the processes of natural selection. But plants, like animals are still organic. They cannot produce chemicals of such toxicity that in killing animals they kill themselves. Thus they sometimes produce chemicals that will merely scare some animals off. Various chillies contains chemicals that result in sensible animals (non-Mexicans) not coming back for a second bite. Marijuana plants, poppies and the coca plant contain chemicals that cause animals that eat them some cause for not returning.
Some of the chemicals have different effects in different animals … poisonous to one, beneficial to another, toxic to tumour cells benign to other cells, inducing addictive euphoria in one species and having no effect on another.
They are there. They are part of the biological struggle between species on earth. It is difficult to see how they can ever be eradicated.
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